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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX59
All Species:
11.82
Human Site:
S146
Identified Species:
17.33
UniProt:
Q5T1V6
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1V6
NP_001026895.2
619
68810
S146
V
K
E
K
E
E
K
S
K
L
S
N
P
Q
K
Chimpanzee
Pan troglodytes
XP_001143546
619
68778
S146
V
K
E
K
E
E
K
S
K
L
S
N
P
Q
K
Rhesus Macaque
Macaca mulatta
XP_001109688
319
35696
Dog
Lupus familis
XP_537128
620
68704
L147
V
K
E
K
E
E
R
L
K
L
S
A
P
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBN9
619
68216
L146
V
K
E
G
E
G
S
L
R
P
S
S
P
Q
R
Rat
Rattus norvegicus
Q66HG7
589
65047
L146
V
K
E
E
E
G
S
L
K
P
S
S
P
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520980
538
59378
S136
K
T
D
V
D
V
C
S
L
E
C
K
A
K
H
Chicken
Gallus gallus
XP_422189
625
69278
L151
M
Q
E
K
E
E
K
L
K
S
A
H
L
A
K
Frog
Xenopus laevis
NP_001106297
254
27959
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
T273
E
E
E
V
D
L
Q
T
A
L
T
G
F
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
R199
V
E
D
V
E
R
K
R
E
F
Y
I
P
P
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198909
620
68882
I165
K
E
D
V
Q
K
D
I
Q
E
A
E
N
P
E
Poplar Tree
Populus trichocarpa
XP_002320399
524
57616
D121
V
K
G
D
S
V
P
D
P
I
L
S
F
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3EBD3
505
55199
S103
I
H
V
Q
G
Q
G
S
A
V
P
P
P
V
L
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
I140
K
F
D
N
Y
D
N
I
P
V
D
A
S
G
K
Red Bread Mold
Neurospora crassa
Q7SEL0
728
82594
Y239
G
E
E
R
A
R
Q
Y
L
E
Q
H
R
R
I
Conservation
Percent
Protein Identity:
100
99
51
89.8
N.A.
83.6
79.8
N.A.
61.8
72.3
30.2
22.3
N.A.
27.6
N.A.
N.A.
32.1
Protein Similarity:
100
99.8
51.3
93.3
N.A.
89.6
86.7
N.A.
71.5
84.3
35.3
37.3
N.A.
45.8
N.A.
N.A.
52.4
P-Site Identity:
100
100
0
73.3
N.A.
46.6
53.3
N.A.
6.6
46.6
0
20
N.A.
26.6
N.A.
N.A.
0
P-Site Similarity:
100
100
0
80
N.A.
66.6
66.6
N.A.
26.6
73.3
0
53.3
N.A.
53.3
N.A.
N.A.
46.6
Percent
Protein Identity:
40.7
N.A.
N.A.
38.1
26.3
26.9
Protein Similarity:
58
N.A.
N.A.
56.2
46.3
46.4
P-Site Identity:
13.3
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
26.6
N.A.
N.A.
40
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
13
0
13
13
7
7
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
25
7
13
7
7
7
0
0
7
0
0
0
0
% D
% Glu:
7
25
50
7
44
25
0
0
7
19
0
7
0
0
13
% E
% Phe:
0
7
0
0
0
0
0
0
0
7
0
0
13
0
0
% F
% Gly:
7
0
7
7
7
13
7
0
0
0
0
7
0
7
7
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
13
0
7
7
% H
% Ile:
7
0
0
0
0
0
0
13
0
7
0
7
0
0
7
% I
% Lys:
19
38
0
25
0
7
25
0
32
0
0
7
0
7
32
% K
% Leu:
0
0
0
0
0
7
0
25
13
25
7
0
7
0
7
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
7
0
0
0
0
13
7
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
13
13
7
7
44
13
0
% P
% Gln:
0
7
0
7
7
7
13
0
7
0
7
0
0
32
0
% Q
% Arg:
0
0
0
7
0
13
7
7
7
0
0
0
7
7
7
% R
% Ser:
0
0
0
0
7
0
13
25
0
7
32
19
7
7
7
% S
% Thr:
0
7
0
0
0
0
0
7
0
0
7
0
0
0
7
% T
% Val:
44
0
7
25
0
13
0
0
0
13
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
7
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _